Full length protein, corresponding to amino acids 1-323 of Human HDC2/ PHC2 (NP_004418.2).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml;
Target
Alternative Names
PHC2; polyhomeotic homolog 2 (Drosophila); PH2; EDR2; HPH2; polyhomeotic-like protein 2; polyhomeotic 2; polyhomeotic-like 2; early development regulatory protein 2; early development regulator 2 (homolog of polyhomeotic 2);
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys-119, rendering chromatin heritably changed in its expressibility.
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