Anti-HCLS1 monoclonal antibody (DMABT-H13893)
Mouse anti-Human HCLS1 monoclonal antibody for WB, IHC, sELISA, ELISA
Datasheet
Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
3B7
Species Reactivity
Human
Immunogen
HCLS1 (AAH16758, 266 a.a. ~ 355 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Target
Alternative Names
HCLS1; hematopoietic cell-specific Lyn substrate 1; hematopoietic lineage cell-specific protein; cortactin like; CTTNL; HS1
Entrez Gene ID
UniProt ID
Product Background
Antigen Description
Hematopoietic lineage cell-specific protein is a protein that in humans is encoded by the HCLS1 gene. 0The function about HCLS1 antigen include DNA binding; SH3 domain binding; protein complex binding; sequence-specific DNA binding transcription factor activity.
Pathway
B Cell Receptor Signaling Pathway, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; Fc-epsilon receptor I signaling in mast cells, organism-specific biosystem; IL-5 Signaling Pathway, organism-specific biosystem; Pathogenic Escherichia coli infection, organism-specific biosystem; Pathogenic Escherichia coli infection, conserved biosystem.
Citations
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References
Hao, JJ; Carey, GB; et al. Syk-mediated tyrosine phosphorylation is required for the association of hematopoietic lineage cell-specific protein 1 with lipid rafts and B cell antigen receptor signalosome complex. JOURNAL OF BIOLOGICAL CHEMISTRY 279:33413-33420(2004).
Ruzzene, M; Brunati, AM; et al. SH2 domains mediate the sequential phosphorylation of HS1 protein by p72(syk) and Src-related protein tyrosine kinases. BIOCHEMISTRY 35:5327-5332(1996).
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Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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