Anti-HCLS1 monoclonal antibody (DMABT-H13893)
Mouse anti-Human HCLS1 monoclonal antibody for WB, IHC, sELISA, ELISA
Datasheet
Bring this labeled antibody directly to your bench!
Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
3B7
Species Reactivity
Human
Immunogen
HCLS1 (AAH16758, 266 a.a. ~ 355 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Target
Alternative Names
HCLS1; hematopoietic cell-specific Lyn substrate 1; hematopoietic lineage cell-specific protein; cortactin like; CTTNL; HS1
Entrez Gene ID
UniProt ID
Product Background
Antigen Description
Hematopoietic lineage cell-specific protein is a protein that in humans is encoded by the HCLS1 gene. 0The function about HCLS1 antigen include DNA binding; SH3 domain binding; protein complex binding; sequence-specific DNA binding transcription factor activity.
Pathway
B Cell Receptor Signaling Pathway, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; Fc-epsilon receptor I signaling in mast cells, organism-specific biosystem; IL-5 Signaling Pathway, organism-specific biosystem; Pathogenic Escherichia coli infection, organism-specific biosystem; Pathogenic Escherichia coli infection, conserved biosystem.
Citations
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References
Ruzzene, M; Brunati, AM; et al. SH2 domains mediate the sequential phosphorylation of HS1 protein by p72(syk) and Src-related protein tyrosine kinases. BIOCHEMISTRY 35:5327-5332(1996).
Hao, JJ; Carey, GB; et al. Syk-mediated tyrosine phosphorylation is required for the association of hematopoietic lineage cell-specific protein 1 with lipid rafts and B cell antigen receptor signalosome complex. JOURNAL OF BIOLOGICAL CHEMISTRY 279:33413-33420(2004).
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Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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