Tag/Conjugate
Unconjugated
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
soluble guanylate cyclase subunit that forms a heterodimer with Gucy1b3; may also function as an intracellular nitric oxide receptor
Function
GTP binding; guanylate cyclase activity; guanylate cyclase activity; guanylate cyclase activity; heme binding; ion binding; nucleotide binding; protein heterodimerization activity;
Synonyms
GUCY1A3; guanylate cyclase 1, soluble, alpha 3; SGC; Gucy1a1; guanylate cyclase soluble subunit alpha-3; GCS-alpha-1; GCS-alpha-3; soluble guanylate cyclase large subunit; Guanylate cyclase soluble alpha 1 (GTP pyrophosphate - lyase); Guanylate cyclase, soluble, alpha 1 (GTP pyrophosphate - lyase);
Citations
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Iino, S; Horiguchi, K; et al. Interstitial cells of Cajal contain signalling molecules for transduction of nitrergic stimulation in guinea pig caecum. NEUROGASTROENTEROLOGY AND MOTILITY 21:553-563(2009).
Wang, YR; Kramer, S; et al. Stimulation of soluble guanylate cyclase slows progression in anti-thy1-induced chronic glomerulosclerosis. KIDNEY INTERNATIONAL 68:47-61(2005).
COA
Certificate of Analysis
