Sample
Serum, Plasma-EDTA, Plasma-Heparin, Plasma-Citrate
Intended Use
This ELISA kit is used for quantitative determination of rat GLP-2 [both GLP-2 (1-33) and GLP-2 (3-33)] in serum or plasma samples. The kit is characterized for sensitive quantification, high specificity and no influences with other components in samples. Rat GLP-2 standard is highly purified synthetic product.
Contents of Kit
1. Rat GLP-2 standard
2. Labeled antigen
3. Rat GLP-2 antibody
4. SA-HRP solution
5. Substrate buffer
6. OPD tablet
7. Stopping solution
8. Buffer solution
9. Washing solution
Storage
Store the complete kit at 2-8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
Detection Range
0.137-100 ng/ml
General Description
The proglucagon gene is expressed in both pancreatic A cell and intestinal L cell. Tissue-specific posttranslational processing of proglucagon by the prohormone convertase produced the different proglucagon derived peptides (PGDPs) in both pancreas and intestine. The most notable pancreatic PGDP is glucagon, whereas the L cell produces several structurally related peptides, including glucagon-like peptide 1 (GLP-1) and GLP-2, as well as glicentin and oxyntomodulin, which contain glucagon sequence in their molecules. Among PGDPs, GLP-2 has recently been found to show intestinal epithelial proliferation.
Citations
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