General Notes
This product (Catalog No. CABT-BL1703) is a rabbit-derived IgG polyclonal antibody raised against human GTF2H4, targeting the amino acid region 381–462 of the protein. This antibody exhibits cross-reactivity with GTF2H4 from mouse, rat, dog, pig, cow, horse, rabbit, and sheep. It has been affinity purified by protein A. This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
CABT-BL1703 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500), ICC/IF (1:100–1:500), ELISA (1:5,000–1:10,000) applications.
CABT-BL1703 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Alternative Names
Basic transcription factor 2 52 kDa subunit; Basic transcription factor 52 kDa subunit; BTF2 p52; General transcription factor IIH polypeptide 4 52kDa; General transcription factor IIH polypeptide 4 52kDa subunit; General transcription factor IIH polypeptide 4 52kDa variant; General transcription factor IIH polypeptide 4; General transcription factor IIH subunit 4; Gtf2h4; OTTHUMP00000029049; OTTHUMP00000164874; P52; TF2H4_HUMAN; TFB2; TFIIH basal transcription factor complex p52 subunit; TFIIH protein; TIFIIH; Transcription factor II H; Transcription factor IIH 52 kDa subunit