Product Overview
Blocking/Immunizing peptide for anti-GOT2 (aa 295 to 306) antibody
Target
GOT2 (aa 295 to 306)
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene.
Function
L-aspartate:2-oxoglutarate aminotransferase activity; L-aspartate:2-oxoglutarate aminotransferase activity; L-aspartate:2-oxoglutarate aminotransferase activity; L-phenylalanine:2-oxoglutarate aminotransferase activity; pyridoxal phosphate binding;
Synonyms
GOT2; glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2); aspartate aminotransferase, mitochondrial; KAT4; KATIV; kynurenine aminotransferase IV; mitAAT; FABP-1; FABPpm; mAspAT; transaminase A; fatty acid-binding protein; glutamate oxaloacetate transaminase 2; plasma membrane-associated fatty acid-binding protein; FLJ40994;
Citations
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LUCASSON, JF; MCNAB, D; et al. HSV-2 INCREASES THE MITOCHONDRIAL ASPARTATE AMINO TRANSAMINASE CHARACTERISTIC OF TUMOR-CELLS. VIROLOGY 205:393-405(1994).
STUMP, DD; ZHOU, SL; et al. COMPARISON OF PLASMA-MEMBRANE FABP AND MITOCHONDRIAL ISOFORM OF ASPARTATE-AMINOTRANSFERASE FROM RAT-LIVER. AMERICAN JOURNAL OF PHYSIOLOGY 265:G894-G902(1993).