Anti-GCH1 monoclonal antibody (DMABT-H13826)
Mouse anti-Human GCH1 monoclonal antibody for WB, IHC, IP, sELISA, ELISA
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GCH1 (NP_000152, 84 a.a. ~283a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
GCH1; GTP cyclohydrolase 1; dystonia25, DYT5, DYT14, GCH; dopa responsive dystonia; DYT5a; GTPCH1
Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nitric oxide, organism-specific biosystem; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, organism-specific biosystem; eNOS activation and regulation, organism-specific biosystem;
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Liu, X; Zhang, SS; et al. GCH1 Mutation and Clinical Study of Chinese Patients with Dopa-responsive Dystonia. MOVEMENT DISORDERS 25:447-451(2010).
Souza, CP; Valadares, ER; et al. Mutation in intron 5 of GTP cyclohydrolase 1 gene causes dopa-responsive dystonia (Segawa syndrome) in a Brazilian family. GENETICS AND MOLECULAR RESEARCH 7:687-694(2008).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.