Anti-GCH1 monoclonal antibody (DMABT-H13826)

Mouse anti-Human GCH1 monoclonal antibody for WB, IHC, IP, sELISA, ELISA Datasheet

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Host Species
Antibody Isotype
Species Reactivity
GCH1 (NP_000152, 84 a.a. ~283a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.


Alternative Names
GCH1; GTP cyclohydrolase 1; dystonia25, DYT5, DYT14, GCH; dopa responsive dystonia; DYT5a; GTPCH1
Entrez Gene ID
UniProt ID

Product Background

Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nitric oxide, organism-specific biosystem; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, organism-specific biosystem; eNOS activation and regulation, organism-specific biosystem;


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Furuya, H; Murai, H; et al. A case of late-onset Segawa syndrome (autosomal dominant dopa-responsive dystonia) with a novel mutation of the GTP-cyclohydrase I (GCH1) gene. CLINICAL NEUROLOGY AND NEUROSURGERY 108:784-786(2006).
Muller, U; et al. The monogenic primary dystonias. BRAIN 132:2005-2025(2009).

Custom Antibody Labeling

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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