Human FZD8 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-FZD8/frizzled 8 antibody

Target

FZD8 / frizzled 8

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]

Function

G-protein coupled receptor activity; PDZ domain binding; Wnt-activated receptor activity; Wnt-activated receptor activity; Wnt-protein binding; protein binding; receptor binding; ubiquitin protein ligase binding;

Synonyms

FZD8; frizzled class receptor 8; FZ-8; hFZ8; frizzled-8; frizzled homolog 8; frizzled family receptor 8; frizzled 8, seven transmembrane spanning receptor;