Human FREM1 blocking peptide

Product Overview

Blocking peptide for anti-FREM1 antibody

Target

FREM1

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.

Format

Liquid

Concentration

200 μg/ml

Buffer

PBS containing 0.02% sodium azide

Preservative

0.02% Sodium Azide

Storage

Store at -20℃, stable for one year.

Entrez Gene ID

Antigen Description

This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.

Function

binding; metal ion binding; sugar binding;

Synonyms

FREM1; FRAS1 related extracellular matrix 1; C9orf154, chromosome 9 open reading frame 154; FRAS1-related extracellular matrix protein 1; C9orf143; C9orf145; DKFZp686M16108; FLJ25461; TILRR; extracellular matrix protein QBRICK; BNAR; MOTA; TRIGNO2; C9orf154;