Synthetic Human FREM1 blocking peptide for BL
Blocking peptide for anti-FREM1 antibody
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
PBS containing 0.02% sodium azide
Store at -20oC, stable for one year.
This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.
binding; metal ion binding; sugar binding;
FREM1; FRAS1 related extracellular matrix 1; C9orf154, chromosome 9 open reading frame 154; FRAS1-related extracellular matrix protein 1; C9orf143; C9orf145; DKFZp686M16108; FLJ25461; TILRR; extracellular matrix protein QBRICK; BNAR; MOTA; TRIGNO2; C9orf154;