Product Overview
Blocking/Immunizing peptide for anti-FOXO4/MLLT7 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.
Function
DNA binding; DNA binding, bending; double-stranded DNA binding; enzyme binding; protein binding; protein kinase binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific distal enhancer binding
Synonyms
FOXO4; forkhead box O4; MLLT7, myeloid/lymphoid or mixed lineage leukemia (trithorax (Drosophila) homolog); translocated to, 7 , myeloid/lymphoid or mixed lineage leukemia (trithorax homolog, Drosophila); translocated to, 7; forkhead box protein O4; AFX1; fork head domain transcription factor AFX1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7; AFX; MLLT7; MGC120490;
Citations
Publication ()
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