Human FOXN1 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-FOXN1 antibody

Target

FOXN1

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed.

Function

DNA binding, bending; double-stranded DNA binding; sequence-specific DNA binding; sequence-specific distal enhancer binding RNA polymerase II transcription factor activity; transcription factor binding;

Synonyms

FOXN1; forkhead box N1; RONU, Rowett nude , WHN, winged helix nude; forkhead box protein N1; FKHL20; Rowett nude; winged helix nude; winged-helix nude; winged-helix transcription factor nude; WHN; RONU;