Human FOXN1 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

FOXN1 peptide corresponds to 14 amino acids of FOXN1.

Purity

> 95 % by SDS-PAGE.

Format

Lyophilized

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Reconstitution

FOXN1 peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.

Introduction

Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5 UTR of this gene has been observed. [provided by RefSeq, Jul 2008]

Entrez Gene ID

Synonyms

FOXN1; forkhead box N1; WHN; RONU; FKHL20; forkhead box protein N1; Rowett nude; winged helix nude; winged-helix nude; winged-helix transcription factor nude;