Product Overview
Blocking/Immunizing peptide for anti-FBL2/FBXL2 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Function
protein binding; ubiquitin-protein ligase activity;
Synonyms
FBXL2; F-box and leucine-rich repeat protein 2; F-box/LRR-repeat protein 2; FBL2; FBL3; F-box protein FBL2/FBL3; F-box protein containing leucine-rich repeats; DKFZp564P0622;
Citations
Publication ()
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