This gene encodes an ankyrin repeat protein that belongs to the death receptor-associated family of proteins and plays a role in mediating apoptosis. The encoded protein is also thought to function in the replication stress-induced checkpoint signaling pathway via interaction with checkpoint kinase 1. [provided by RefSeq, Aug 2013]
Function
death receptor binding; death receptor binding; protein binding; ubiquitin-protein transferase activity
Synonyms
FEM1B; fem-1 homolog b (C. elegans); F1AA; F1A-ALPHA; FEM1-beta; protein fem-1 homolog B; FEM-1-like death receptor binding protein; fem-1-like in apoptotic pathway protein alpha; fem-1-like death receptor-binding protein alpha
Citations
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