Synthetic FEM1B blocking peptide for BL
Widely expressed. Highly expressed in testis. Weakly expressed in other tissues.
Belongs to the fem-1 family.Contains 8 ANK repeats.Contains 1 TPR repeat.
Cytoplasm. Nucleus. In the nucleus, the protein level increased slightly after camptothecin (CPT) treatment. Associated with chromatin.
Preservative: 0.02% Sodium Azide Constituents: 0.1% BSA, PBS, pH 7.2
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Preservative: 0.02% Sodium Azide Constituents: 0.1% BSA, PBS, pH 7.2
This gene encodes an ankyrin repeat protein that belongs to the death receptor-associated family of proteins and plays a role in mediating apoptosis. The encoded protein is also thought to function in the replication stress-induced checkpoint signaling pathway via interaction with checkpoint kinase 1. [provided by RefSeq, Aug 2013]
death receptor binding; death receptor binding; protein binding; ubiquitin-protein ligase activity;
FEM1B; fem-1 homolog b (C. elegans); F1AA; F1A-ALPHA; FEM1-beta; protein fem-1 homolog B; FEM-1-like death receptor binding protein; fem-1-like in apoptotic pathway protein alpha; fem-1-like death receptor-binding protein alpha;