This gene encodes a member of a family of transcription factors which regulate the expression of genes required for progression through the cell cycle. The encoded protein regulates progression from G1 to S phase by ensuring the nucleus divides at the proper time. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Function
DNA binding; sequence-specific DNA binding transcription factor activity;
Synonyms
E2F8; E2F transcription factor 8; transcription factor E2F8; FLJ23311; E2F family member 8; E2F-8;
Citations
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