Recombinant full length protein corresponding to Human E2F8 aa 1-867.Sequence: MENEKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKE GSQGEPWTPTANLKMLISAVSPEIRNRDQKRGLFDNRSGLPEAKDCIHEH LSGDEFEKSQPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEEL NVERRRIYDIVNVLESLHMVSRL
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/50 - 1/200; WB: 1/500 - 1/2000.
Target
Alternative Names
E2F8; E2F transcription factor 8; transcription factor E2F8; FLJ23311; E2F family member 8; E2F-8;
Along with E2F7, inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5-TTTC[CG]CGC-3. Directly represses E2F1 transcription. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.
Citations
Publication ()
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