Mouse DTNBP1 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

Purity

> 95 % by SDS-PAGE.

Format

Lyophilized

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Reconstitution

Mouse peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.

Introduction

The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. May be required for normal dopamine homeostasis in the cerebral cortex, hippocampus, and hypothalamus. Plays a role in the regulation of cell surface exposure of DRD2. Contributes to the regulation of dopamine signaling. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation.

Entrez Gene ID

Synonyms

DTNBP1; dystrobrevin binding protein 1; sdy; Bloc1s8; AW048963; dysbindin; 5430437B18Rik; dysbindin; sandy; dysbindin-1; BLOC-1 subunit 8; HPS7 protein homolog; dystrobrevin-binding protein 1; hermansky-Pudlak syndrome 7 protein homolog; biogenesis of lysosome-related organelles complex 1 subunit 8;