Mouse DPM2 blocking peptide (CDBP1042)

Synthetic Mouse DPM2 blocking peptide for Apuri, BL, ELISA Datasheet

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Product Overview
Blocking/Immunizing peptide for anti-Dpm2 (mouse) antibody
Target
Dpm2 (mouse)
Nature
Synthetic
Species Reactivity
Mouse
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Size
100 μg
Storage
Shipped at ambient temperature, store at -20°C.
UniProt ID
Antigen Description
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1.
Function
dolichyl-phosphate beta-D-mannosyltransferase activity; enzyme regulator activity; protein binding; transferase activity; transferase activity, transferring glycosyl groups;
Synonyms
DPM2; dolichol-phosphate (beta-D) mannosyltransferase 2; dolichol phosphate-mannose biosynthesis regulatory protein; R75484; AW557993;

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