Product Overview
Dipyrone, HRP conjugate
Storage
2-8°C short term, -20°C long term
Introduction
Metamizole sodium or dipyrone is a powerful analgesic and antipyretic. It is marketed under various trade names, including Algozone, Algocalmin, Analgin, Dipirona, Novalgin, Neo-Melubrina and Optalgin. Metamizole was first synthesized by the German company Hoechst AG (now part of Sanofi) in 1920, and its mass production started in 1922. It remained available worldwide until the 1970s, when it was discovered that the drug carries a small risk of causing agranulocytosis - a potentially fatal condition. Controversy remains regarding the level of risk. Several national medical authorities have banned metamizole either totally or have restricted it to be available only on prescription, while others have maintained its availability over the counter.
Antigen Description
Dipyrone or "Mexican aspirin" is a nonsteroidal anti-inflammatory drug. The mechanism of action of dipyrone is thought to be similar to that of other NSAIDs: inhibition of the production of prostaglandins. Dipyrone is not approved for use in many countries (including USA, UK) because of fears about agranulocytosis, though this is contraversial. However sales of the drug continue in Mexico and other developing countries.
Keywords
dipyrone; Analgin; Metamizole sodium; Methampyrone
Citations
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