The antibody binds specifically to Der p 7, a house dust mite allergen which plays an important role in inflammatory and hypersensitive reactions. The antibody XI0 binds to an epitope which is overlapping with that of IgE, thereby inhibiting its binding by up to 60%. By preventing mast cell degranulation, the antibody can be useful in the development of hypoallergenic vaccines.
Target
Alternative Names
Mite allergen Der p 7; Allergen Der p VII; Allergen Der p 7; House dust mite; Dermatophagoides spp. Allergens; asthma; Dermatophagoides pteronyssinus
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