D. rerio EFNB2A [Fc]

Nature

Recombinant

Tag/Conjugate

Fc

Application Notes

Measured by its binding ability in a functional ELISA.
Immobilized human EphB4-His at 10 μg/ml (100 μl/well) can bind zebrafish EFNB2A-Fc, The EC50 of zebrafish EFNB2Ais 12.8-30.1 ng/ml.

Purity

(16.2+75.4) % as determined by SDS-PAGE

Preservative

None

Storage

Store it under sterile conditions at -70 °C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Introduction

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008]

Keywords

EFNB2; ephrin-B2; HTKL; EPLG5; Htk-L; LERK5; LERK-5; HTK ligand; ligand of eph-related kinase 5; eph-related receptor tyrosine kinase ligand 5;