Anti-EFNB2 (internal region) polyclonal antibody

Species Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide corresponding to amino acids at internal region of human EFNB2. The sequence is CPKVDSKTVGQYE

Conjugate

Application Notes

ELISA: 1:16000; WB: 0.1-0.3 μg/mL. & The optimal working dilution should be determined by the end user.

Alternative Names

EFNB2; ephrin-B2; HTKL; EPLG5; Htk-L; LERK5; LERK-5; HTK ligand; ligand of eph-related kinase 5; eph-related receptor tyrosine kinase ligand 5;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.

Pathway

Axon guidance; EPHB forward signaling; EphrinB-EPHB pathway;