Human OTUD5 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-DUBA antibody

Target

DUBA

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]

Function

ubiquitin-specific protease activity;

Synonyms

OTUD5; OTU deubiquitinase 5; DUBA; OTU domain-containing protein 5; OTU domain containing 5; deubiquinating enzyme A; deubiquitinating enzyme A;