Human RNF19A blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-DORFIN/RNF19 antibody

Target

DORFIN / RNF19

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Function

ligase activity; transcription factor binding; zinc ion binding;

Synonyms

RNF19A; ring finger protein 19A, RBR E3 ubiquitin protein ligase; RNF19; E3 ubiquitin-protein ligase RNF19A; double ring-finger protein; ring-IBR-ring domain containing protein Dorfin; ring finger protein 19A, E3 ubiquitin protein ligase; protein p38 interacting with transcription factor Sp1;