Synthetic Human DOK1 blocking peptide for BL, WB
Expressed in pancreas, heart, leukocyte and spleen. Expressed in both resting and activated peripheral blood T-cells.
Belongs to the DOK family. Type A subfamily.Contains 1 IRS-type PTB domain.Contains 1 PH domain.
Cytoplasm and Cytoplasm > perinuclear region.
The PTB domain mediates receptor interaction.
Preservative: 0.02% Sodium Azide Constituents: 0.01% BSA, PBS, pH 7.2
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. Preservative: 0.02% Sodium Azide Constituents: 0.01% BSA, PBS, pH 7.2
The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
insulin receptor binding; protein binding; receptor signaling protein activity;
DOK1; docking protein 1, 62kDa (downstream of tyrosine kinase 1); P62DOK; docking protein 1; pp62; p62(dok); Downstream of tyrosine kinase 1; docking protein 1 (downstream of tyrosine kinase 1);