Product Overview
DNase II ( C - term ) peptide ( human )
Tag/Conjugate
Unconjugated
Buffer
PBS with 0.1% BSA 0.02% sodium azide pH7.2
Preservative
0.02% Sodium Azide
Storage
Upon Receipt - Keep as concentrated solution. Aliquot and store at -20℃ or below. Avoid freeze-thaw cycles.
Antigen Description
This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.
Function
DNA binding; deoxyribonuclease II activity; endodeoxyribonuclease activity; hydrolase activity;
Synonyms
DNASE2; deoxyribonuclease II, lysosomal; DNL, DNL2; deoxyribonuclease-2-alpha; R31240_2; acid DNase; DNase II alpha; lysosomal DNase II; DNase II, lysosomal; deoxyribonuclease II alpha; DNL; DNL2; DNASE2A;
Citations
Publication ()
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