Specifications
Immunogen
A synthetic peptide of human DNASE2 is used for rabbit immunization.
Target
Alternative Names
DNASE2; deoxyribonuclease II, lysosomal; DNL, DNL2; deoxyribonuclease-2-alpha; R31240_2; acid DNase; DNase II alpha; lysosomal DNase II; DNase II, lysosomal; deoxyribonuclease II alpha; DNL; DNL2; DNASE2A;
Product Background
Antigen Description
This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.
Pathway
Clathrin derived vesicle budding, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Lysosome Vesicle Biogenesis, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; trans-Golgi Network Vesicle Budding, organism-specific biosystem.
Citations
Publication ()
Have you cited DCABH-11307 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
