Product Overview
Blocking/Immunizing peptide for anti-DLG1 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene, but the full-length nature of some of the variants is not known. [provided by RefSeq, Feb 2011]
Function
L27 domain binding; cytoskeletal protein binding; guanylate kinase activity; ion channel binding; mitogen-activated protein kinase kinase binding; phosphatase binding; phosphoprotein phosphatase activity; potassium channel regulator activity; potassium ch
Synonyms
DLG1; discs, large homolog 1 (Drosophila); hdlg; DLGH1; SAP97; SAP-97; dJ1061C18.1.1; disks large homolog 1; presynaptic protein SAP97; synapse-associated protein 97;
Citations
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Hawkins, ED; Oliaro, J; et al. Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity. NATURE COMMUNICATIONS 4:-(2013).
Aoyagi, T; Takahashi, M; et al. The PDZ domain binding motif (PBM) of human T-cell leukemia virus type 1 Tax can be substituted by heterologous PBMs from viral oncoproteins during T-cell transformation. VIRUS GENES 40:193-199(2010).