Anti-DLG1 monoclonal antibody, clone SQJ 208.5

Antibody Isotype

IgG1

Clone

SQJ 208.5

Species Reactivity

Mouse; Rat

Immunogen

N-Terminal truncated recombinant rat SAP97 tagged fusion protein

Conjugate

Application Notes

WB: 1/1000;

Alternative Names

DLG1; discs, large homolog 1 (Drosophila); disks large homolog 1; SAP-97; synapse-associated protein 97; Drosophila discs-large tumor suppressor homologue (synapse associated protein); Dlgh1; SAP97;

Entrez Gene ID

UniProt ID

Antigen Description

Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel.

Pathway

Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; L1CAM interactions, organism-specific biosystem; NrCAM interactions, organism-specific biosystem; T Cell Receptor Signaling Pathway, organism-specific biosystem;