Synthetic Human DGCR8 blocking peptide for Apuri, BL, ELISA
Blocking/Immunizing peptide for anti-DGCR8 antibody
Human, Mouse, Dog, Rat
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Shipped at ambient temperature, store at -20°C.
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.
double-stranded RNA binding; metal ion binding; protein binding;
DGCR8; DiGeorge syndrome critical region gene 8; C22orf12, chromosome 22 open reading frame 12; microprocessor complex subunit DGCR8; DGCRK6; Gy1; pasha; DiGeorge syndrome critical region 8; C22orf12;