Product Overview
Recombinant dengue 2 premembrane is a whole length peptide expressed from E. coil with 18kDa in size. PreM is considered as a signal peptide responsible for dengue envelope translocation in cells. Experiment showed it can elicit protective immune response, it is considered as a potentialtarget for vaccine development. Recombinant dengue 2 PreM is fused with a 6xHis tag.
Alternative Names
DENV; DENV PreM Protein; DENV PreM; Dengue virus; Dengue virus PreM; DENV-2 PreM; DENV-2
Purity
Protein is >95% pure as determined by 12% PAGE (coomassie staining).
Preservative
0.05% Sodium Azide
Storage
Recombinant dengue 2 premembrane although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Introduction
Dengue virus (DENV) in one of four serotypes is the cause of dengue fever. It is a mosquito-borne single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. All four serotypes can cause the full spectrum of disease. Its genome is about 11000 bases that codes for three structural proteins, capsid protein C, membrane protein M, envelope protein E; seven nonstructural proteins, NS1, NS2a, NS2b, NS3, NS4a, NS4b, NS5; and short non-coding regions on both the 5' and 3' ends. Further classification of each serotype into genotypes often relates to the region where particular strains are commonly found or were first found.
Keywords
DENV; DENV PreM Protein; DENV PreM; Dengue virus; Dengue virus PreM; DENV-2 PreM; DENV-2
Citations
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COA![The purity of Recombinant DENV type 4 NS2B-NS3 (Fragment) [His] >85%, determined by SDS-PAGE](https://resource.creative-diagnostics.com/diagnostics/productimages-1/DAGA-1069-1.jpg)
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