Dengue Protein is >90% pure as determined by 10% PAGE (coomassie staining).
Format
Liquid
Buffer
20mM Tris-Hcl pH 8.0, 8M urea and 60mM NaCl.
Preservative
None
Storage
Dengue although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Introduction
NS1 is one of 7 Dengue Virus non-structural proteins which are thought to be involved in viral replication. NS1 exists as a monomer in its immature form but is rapidly processed in the endoplasmic reticulum to form a stable dimer. A small amount of NS1 remains associated with intracellular organelles where it is thought to be involved in viral replication. The rest of NS1 is found either associated with the plasma membrane or secreted as a soluble hexadimer. NS1 is essential for viral viability but its precise biological function is unknown. Antibodies raised in response to NS1 in viral infection can cross react with cell surface antigens on epithelial cells and platelets and this has been implicated in the development of Dengue Hemorrhagic fever.
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COA
Publication ![The purity of Recombinant DENV type 4 NS2B-NS3 (Fragment) [His] >85%, determined by SDS-PAGE](https://resource.creative-diagnostics.com/diagnostics/productimages-1/DAGA-1069-1.jpg)
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