DDX3X blocking peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

Format

Liquid

Concentration

200 μg/mL

Preservative

None

Storage

-20°C

Gene ID

1654

UniProt ID

O00571

Antigen Description

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. This gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]

Function

ATP binding; ATP-dependent DNA helicase activity; ATP-dependent RNA helicase activity; ATPase activity; DNA binding; RNA binding; RNA stem-loop binding; eukaryotic initiation factor 4E binding; mRNA 5'-UTR binding; poly(A) RNA binding; poly(A) binding; protein binding; ribosomal small subunit binding; transcription factor binding; translation initiation factor binding

Synonyms

DDX3X; DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked; DBX; DDX3; HLP2; DDX14; ATP-dependent RNA helicase DDX3X; CAP-Rf; DEAD/H box-3; DEAD box, X isoform; helicase like protein 2; helicase-like protein 2; DEAD box protein 3, X-chromosomal; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked