Anti-DDX3X monoclonal antibody, clone JNH22G22E21

Name: Anti-DDX3X monoclonal antibody, clone JNH22G22E21
SKU: DCABH-3397

Mouse anti-Human DDX3X monoclonal antibody for WB, FC

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COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG2b

Clone

JNH22G22E21

Species Reactivity

Human

Immunogen

Recombinant fragment corresponding to amino acids 24-203 of Human DDX3 (NP_001347).

Conjugate

Unconjugated

Applications

Application Notes

WB: 2 - 5 μg/ml; Flow Cyt: 1μg/10⁶ cells;

Target

Alternative Names

DDX3X; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked; DDX3, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 3; ATP-dependent RNA helicase DDX3X; DBX; DDX14; HLP2; CAP-Rf; DEAD/H box-3; DEAD box, X isoform; helicase like protein 2; helicase-like protein

Entrez Gene ID

1654

UniProt ID

O00571

Product Background

Antigen Description

ATP-dependent RNA helicase. Acts as a cofactor for XPO1-mediated nuclear export of incompletely spliced HIV-1 Rev RNAs. Also involved in HIV-1 replication. Interacts specifically with hepatitis C virus core protein resulting in a change in intracellular location.

Pathway

RIG-I-like receptor signaling pathway, organism-specific biosystem; RIG-I-like receptor signaling pathway, conserved biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem;

Citations