Product Overview
Blocking/Immunizing peptide for anti-DCXR antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010]
Function
L-xylulose reductase (NADP+) activity; nucleotide binding; oxidoreductase activity, acting on CH-OH group of donors; oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;
Synonyms
DCXR; dicarbonyl/L-xylulose reductase; L-xylulose reductase; DCR; KIDCR; SDR20C1; short chain dehydrogenase/reductase family 20C; member 1; carbonyl reductase 2; carbonyl reductase II; sperm surface protein P34H; kidney dicarbonyl reductase; short chain dehydrogenase/reductase family 20C, member 1; XR; HCR2; P34H; HCRII;
Citations
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St-Cyr, A; Legare, C; et al. P26h and dicarbonyl/L-xylouse reductase are two distinct proteins present in the hamster epididymis. MOLECULAR REPRODUCTION AND DEVELOPMENT 69:137-145(2004).
Mittag, A; Lenz, D; et al. Polychromatic (eight-color) slide-based cytometry for the phenotyping of leukocyte, NK, and NKT subsets. CYTOMETRY PART A 65A:103-115(2005).