Mouse anti-Human DCXR polyclonal antibody

Species Reactivity

Human

Immunogen

DCXR (NP_057370, 145 a.a. ~ 244 a.a) partial recombinant protein with GST tag. The sequence is NHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC

Conjugate

Alternative Names

DCXR; dicarbonyl/L-xylulose reductase; XR; DCR; HCR2; P34H; HCRII; KIDCR; PNTSU; SDR20C1; L-xylulose reductase; carbonyl reductase 2; carbonyl reductase II; sperm surface protein P34H; kidney dicarbonyl reductase; short chain dehydrogenase/reductase famil

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010]

Pathway

D-glucuronate degradation I; Pentose and glucuronate interconversions;