Alternative Names
Chloremphenicol; chloramphenicol; Chloromycetin; Chlornitromycin; Levomycetin; CAP
Application Notes
Matched pair antibody available for Chloramphenicol [HRP]: Chloramphenicol antibody (Catalog #
HMABPY040)
Concentration
Batch dependent - please inquire should you have specific requirements.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Introduction
Chloramphenicol is a semisynthetic, broad-spectrum antibiotic derived from Streptomyces venequelae with primarily bacteriostatic activity. Chloramphenicol diffuses through the bacterial cell wall and reversibly binds to the bacterial 50S ribosomal subunit. The binding interferes with peptidyl transferase activity, thereby prevents transfer of amino acids to the growing peptide chains and blocks peptide bond formation. As a result bacterial protein synthesis is blocked and impede bacterial cell proliferation.
Antigen Description
Chloramphenicol HRP Conjugated
Keywords
Chloremphenicol; chloramphenicol; Chloromycetin; Chlornitromycin; Levomycetin; Chloramphenicol HRP conjugate; drug-HRP conjugate, drug-conjugate
Citations
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Antonicelli, F; Parmentier, M; et al. Nacystelyn inhibits oxidant-mediated interleukin-8 expression and NF-kappa B nuclear binding in alveolar epithelial cells. FREE RADICAL BIOLOGY AND MEDICINE 32:492-502(2002).
Galmozzi, E; Tomassetti, A; et al. Exon 3 of the alpha folate receptor gene contains a 5 ' splice site which confers enhanced ovarian carcinoma specific expression. FEBS LETTERS 502:31-34(2001).