Mouse CX3CR1 blocking peptide (CDBP0914)

Synthetic Mouse CX3CR1 blocking peptide for BL, WB

Product Overview
CX3CR1 ( C - term ) peptide ( mouse )
Target
CX3CR1
Nature
Synthetic
Species Reactivity
Mouse
Tag/Conjugate
Unconjugated
Procedure
None
Format
Liquid
Concentration
0.2 mg/ml
Size
50 μg
Buffer
PBS with 0.1% BSA 0.02% sodium azide pH7.2
Preservative
0.02% Sodium Azide
Storage
Upon receipt - Keep as concentrated solution. Aliquot and store at -20℃ or below. Avoid freeze-thaw cycles.
UniProt ID
Antigen Description
Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
Function
C-X3-C chemokine receptor activity; G-protein coupled receptor activity; chemokine receptor activity; protein binding; receptor activity; signal transducer activity;
Synonyms
CX3CR1; chemokine (C-X3-C motif) receptor 1; chemokine (C X3 C) receptor 1 , CMKBRL1, GPR13; CX3C chemokine receptor 1; CCRL1; CMKDR1; V28; CMK-BRL1; CMK-BRL-1; C-X3-C CKR-1; fractalkine receptor; G protein-coupled receptor 13; G-protein coupled receptor 13; chemokine (C-X3-C) receptor 1; beta chemokine receptor-like 1; chemokine (C-C) receptor-like 1; GPR13; GPRV28; CMKBRL1;

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References


Clark, AK; Grist, J; et al. Spinal cathepsin S and fractalkine contribute to chronic pain in the collagen-induced arthritis model. ARTHRITIS AND RHEUMATISM 64:2038-2047(2012).
Haynes, LM; Jones, LP; et al. Enhanced disease and pulmonary eosinophilia associated with formalin-inactivated respiratory syncytial virus vaccination are linked to G glycoprotein CX3C-CX3CR1 interaction and expression of substance P. JOURNAL OF VIROLOGY 77:9831-9844(2003).

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