Human CX3CR1 blocking peptide (CDBP0913)

Synthetic Human CX3CR1 blocking peptide for BL

Product Overview
CX3CR1( extracellular ) peptide ( human )
Target
CX3CR1
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Procedure
None
Concentration
0.2 mg/ml
Size
50 μg
Buffer
PBS with 0.1% BSA 0.02% sodium azide pH7.2
Preservative
0.02% Sodium Azide
Storage
Upon receipt - Keep as concentrated solution. Aliquot and store at -20℃ or below. Avoid freeze-thaw cycles.
UniProt ID
Antigen Description
Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
Function
C-X3-C chemokine receptor activity; G-protein coupled receptor activity; chemokine receptor activity; cytokine receptor activity; receptor activity; signal transducer activity;
Synonyms
CX3CR1; chemokine (C-X3-C) receptor 1; CX3C chemokine receptor 1; C-X3-C CKR-1; fractalkine receptor; C-X3-C chemokine receptor 1;

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References


Shan, S; Hong-Min, T; et al. NEW evidences for fractalkine/CX3CL1 involved in substantia nigral microglial activation and behavioral changes in a rat model of Parkinson's disease. NEUROBIOLOGY OF AGING 32:443-458(2011).
Xuan, WL; Liao, YL; et al. Detrimental effect of fractalkine on myocardial ischaemia and heart failure. CARDIOVASCULAR RESEARCH 92:385-393(2011).

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