Anti-CLTB monoclonal antibody (DMABT-H13454)

Mouse anti-Human CLTB monoclonal antibody for WB, IHC, IF, sELISA, ELISA Datasheet

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Host Species
Antibody Isotype
Species Reactivity
CLTB (AAH06457,2a.a. ~ 211 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.


Alternative Names
CLTB; clathrin, light chain B; clathrin, light polypeptide (Lcb); clathrin light chain B; Lcb; clathrin, light chain (Lcb)
Entrez Gene ID
UniProt ID

Product Background

Gene summary
CLTB (Clathrin Light Chain B) is a Protein Coding gene. Diseases associated with CLTB include leber congenital amaurosis. Among its related pathways are Signaling by GPCR and Lysosome. GO annotations related to this gene include structural molecule activity and peptide binding. An important paralog of this gene is CLTA. Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants.
Antigen Description
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. The function about CLTB antigen include peptide binding; protein binding; structural molecule activity.
Arf1 pathway, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; Endocrine and other factor-regulated calcium reabsorption, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem.


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Salmon-Ceron, D; Excler, JL; et al. Safety and immunogenicity of a live recombinant canarypox virus expressing HIV type 1 gp120 MN tm/gag/protease LAI (ALVAC-HIV, vCP205) followed by a p24E-V3 MN synthetic peptide (CLTB-36) administered in healthy volunteers at low risk for HIV infection. AIDS RESEARCH AND HUMAN RETROVIRUSES 15:633-645(1999).

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