Anti-CLTB monoclonal antibody (DMABT-H13454)

Mouse anti-Human CLTB monoclonal antibody for WB, IHC, IF, sELISA, ELISA Datasheet

Online Inquiry Add to basket

Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
5C23-2F4
Species Reactivity
Human
Immunogen
CLTB (AAH06457,2a.a. ~ 211 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
CLTB; clathrin, light chain B; clathrin, light polypeptide (Lcb); clathrin light chain B; Lcb; clathrin, light chain (Lcb)
Entrez Gene ID
UniProt ID

Product Background


Gene summary
CLTB (Clathrin Light Chain B) is a Protein Coding gene. Diseases associated with CLTB include leber congenital amaurosis. Among its related pathways are Signaling by GPCR and Lysosome. GO annotations related to this gene include structural molecule activity and peptide binding. An important paralog of this gene is CLTA. Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants.
Antigen Description
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. The function about CLTB antigen include peptide binding; protein binding; structural molecule activity.
Pathway
Arf1 pathway, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; Endocrine and other factor-regulated calcium reabsorption, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem.

Citations


Have you cited DMABT-H13454 in a publication? Let us know and earn a reward for your research.

References


Salmon-Ceron, D; Excler, JL; et al. Safety and immunogenicity of a live recombinant canarypox virus expressing HIV type 1 gp120 MN tm/gag/protease LAI (ALVAC-HIV, vCP205) followed by a p24E-V3 MN synthetic peptide (CLTB-36) administered in healthy volunteers at low risk for HIV infection. AIDS RESEARCH AND HUMAN RETROVIRUSES 15:633-645(1999).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !

Online Inquiry

Name
Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: Anti-CLTB monoclonal antibody

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket