Anti-CDKL2 monoclonal antibody (DMABT-H13392)

Mouse anti-Human CDKL2 monoclonal antibody for WB, IHC, IF, sELISA, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
2G7
Species Reactivity
Human
Immunogen
CDKL2 (NP_003939, 394 a.a. ~ 493 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
CDKL2; cyclin-dependent kinase-like 2 (CDC2-related kinase); cyclin-dependent kinase-like 2; KKIAMRE; P56; CDC2-related kinase
Entrez Gene ID
UniProt ID

Product Background


Gene summary
CDKL2 (Cyclin Dependent Kinase Like 2) is a Protein Coding gene. Diseases associated with CDKL2 include joubert syndrome with orofaciodigital defect and meckel syndrome 1. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDKL3. This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus.
Antigen Description
Protein Symbol:Q92772-CDKL2_HUMANRecommended name:Cyclin-dependent kinase-like 2Protein Accession:Q92772Secondary Accessions:B2R695Cyclin-dependent kinase-like 2 is an enzyme that in humans is encoded by the CDKL2 gene. 0The function about CDKL2 antigen include ATP binding; cyclin-dependent protein kinase activity; nucleotide binding; protein kinase activity.

Citations


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References


Tang, L; Gao, YF; et al. Evaluation of Cyclin-Dependent Kinase-Like 1 Expression in Breast Cancer Tissues and Its Regulation in Cancer Cell Growth. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS 27:392-398(2012).
Sassa, T; Gomi, H; et al. Postnatal expression of Cdkl2 in mouse brain revealed by LacZ inserted into the Cdkl2 locus. CELL AND TISSUE RESEARCH 315:147-156(2004).

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