Anti-CDK19 monoclonal antibody (DMABT-H13372)

Mouse anti-Human CDK19 monoclonal antibody for IHC, sELISA, ELISA Datasheet

Bring this labeled antibody directly to your bench!

Online Inquiry Add to basket

Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
4E8
Species Reactivity
Human
Immunogen
CDC2L6 (NP_055891.1,2a.a. ~ 114 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
CDK19; cyclin-dependent kinase 19; CDC2L6, CDK11, cell division cycle 2 like 6 (CDK8 like) , cyclin dependent kinase (CDC2 like) 11; bA346C16.3; KIAA1028; death-preventing kinase
Entrez Gene ID
UniProt ID

Product Background


Gene summary
CDK19 (Cyclin-Dependent Kinase 19) is a Protein Coding gene. Among its related pathways are Metabolism and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDK8. This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Antigen Description
Protein Symbol:Q9BWU1-CDK19_HUMANRecommended name:Cyclin-dependent kinase 19Protein Accession:Q9BWU1Secondary Accessions:Q5JQZ7Q5JR00Q8TC78Q9UPX2The function about CDK19 antigen include ATP binding; cyclin-dependent protein kinase activity; nucleotide binding; protein serine/threonine kinase activity; transferase activity, transferring phosphorus-containing groups.
Pathway
Developmental Biology, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPARA Activates Gene Expression, organism-specific biosystem; Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha), organism-specific biosystem; Transcriptional Regulation of White Adipocyte Differentiation, org.

Citations


Have you cited DMABT-H13372 in a publication? Let us know and earn a reward for your research.

References


Atula, S; Grenman, R; et al. Fibroblasts can modulate the phenotype of malignant epithelial cells in vitro. EXPERIMENTAL CELL RESEARCH 235:180-187(1997).
Kremer, M; Dirnhofer, S; et al. p27(Kip1) immunostaining for the differential diagnosis of small B-cell neoplasms in trephine bone marrow biopsies. MODERN PATHOLOGY 14:1022-1029(2001).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !

Online Inquiry

Name
Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: Anti-CDK19 monoclonal antibody

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket