This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.
Pathway
Developmental Biology; Fatty acid, triacylglycerol, and ketone body metabolism; Metabolism; Metabolism of lipids and lipoproteins; PPARA Activates Gene Expression; Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha); Transcriptional Regulation of White Adipocyte Differentiation;
Citations
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