Human CAD blocking peptide (CDBP0653)

Synthetic Human CAD blocking peptide for BL, WB Datasheet

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Product Overview
DFF40 / CAD peptide ( mouse )
Target
CAD
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Concentration
0.2 mg/ml
Size
50 μg
Buffer
PBS with 0.1% BSA 0.02% sodium azide pH7.2
Storage
Store at 4 °C, stable for one year.
UniProt ID
Antigen Description
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
Function
ATP binding; aspartate binding; aspartate carbamoyltransferase activity; aspartate carbamoyltransferase activity; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; dihydroorotase
Synonyms
CAD; carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; CAD protein; CAD trifunctional protein; multifunctional protein CAD;

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