Human ADRBK1 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-BARK1/GRK2 antibody

Target

BARK1 / GRK2

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]

Function

ATP binding; Edg-2 lysophosphatidic acid receptor binding; G-protein coupled receptor kinase activity; alpha-2A adrenergic receptor binding; beta-adrenergic receptor kinase activity; protein binding; protein kinase activity;

Synonyms

ADRBK1; adrenergic, beta, receptor kinase 1; GRK2; BARK1; BETA-ARK1; beta-adrenergic receptor kinase 1; beta-ARK-1; G-protein coupled receptor kinase 2;