Batch dependent - please inquire should you have specific requirements.
Buffer
50mM PB
Preservative
None
Storage
Store at 2-8°C
Introduction
The initial step in establishing a Bordetella pertussis infection is attachment of the bacteria to the epithelial lining of the host respiratory tract. Two B. pertussis virulence factors are key in this process, filamentous hemagglutinin (FHA) and fimbriae (Fim). Fimbriae are extracellular proteins which like FHA participate in the attachment of bacteria to substrates. Based on their reaction to sera, there are two fimbriae serotypes present in B. pertussis, fimbriae 2 (Fim 2) and fimbriae 3 (Fim 3). Although fimbriae are long structures which serve to tether the bacterial to surfaces, they are composed of subunits which dissociate in SDS producing components with apparent molecular weights of 22,500 and 22,000 Da for Fim 2 and Fim 3, respectively. Interestingly, antibodies raised to native Fim do not react well with SDS-denatured subunits.
Keywords
B. pertussis; Whooping cough; Fimbriae; Fim2; Fim3
Citations
Publication ()
Have you cited DAGB126 in a publication? Let us know and earn a reward for your research.
Q: Have you ever done endotoxin testing on your purified proteins? If so, was that done on this lot of FIM2/3 we are procuring?
A: Confirmed specifications are: LPS less than 0.001%, and Endotoxin less than 5Eu/mg.
Customer Reviews
My Review for B. pertussis Fimbriae 2/3
Creative Diagnostics products are for RESEARCH USE ONLY, please make sure your review is research based.
Required fields are marked with *
Terms and conditions:
We will select high-quality review customers and offer a $30 coupon for your next purchase.
All product reviews must be submitted in the English language.
Creative Diagnostics will not share any personal information of applicants, and all information will be treated with strict confidentiality and will not be sold or disclosed to a third party.
COA
Publication 
Loading ......
