Batch dependent - please inquire should you have specific requirements.
Buffer
20 mM Tris, pH 8.0, 0.1m NaCl, 5 mM B-mercaptoethnaol, 0.25 M imidazole and 6M GdnHCl
Preservative
None
Storage
Store at or below - 20°C
Antigen Description
Pertactin (PRN or p69 protein) is a highly immunogenic virulence factor of Bordetella pertussis, a bacterium that causes pertussis. Specifically, it is an outer membrane protein that promotes adhesion to tracheal epithelial cells. PRN is purified from Bordetella pertussis and is used for the vaccine production as one of the important components of acellular pertussis vaccine. Pertactin domains are common components of the excreted portion of bacterial autotransporter proteins. The domain is made up of a beta helix of variable length. P.69 is produced as a large (910-aa) precursor molecule.
Keywords
B. pertussis
Citations
Publication ()
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