Anti-XPO1 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human XPO1 is used for rabbit immunization.

Conjugate

Alternative Names

XPO1; exportin 1 (CRM1 homolog, yeast); exportin 1 (CRM1, yeast, homolog); exportin-1; CRM1; emb; CRM1, yeast, homolog; chromosome region maintenance 1 protein homolog; exportin-1 (required for chromosome region maintenance); exp1; DKFZp686B1823;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.

Pathway

Canonical NF-kappaB pathway, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cyclin A/B1 associated events during G2/M transition, organism-specific biosystem; DNA Replication, organism-specific biosystem; Disease, organism-specific biosystem; Export of Viral Ribonucleoproteins from Nucleus, organism-specific biosystem;