Anti-XBP1 monoclonal antibody (DCABH-235)
Mouse anti-Human XBP1 monoclonal antibody for WB, ELISA, IHC-P, ICC
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Recombinant fragment, corresponding to amino acids 2-160 of Human XBP1
WB: 0.5 - 1 μg/ml; IHC-P: 10 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
XBP1; X-box binding protein 1; XBP2; X-box-binding protein 1; tax-responsive element-binding protein 5; TREB5
Activation of Chaperone Genes by ATF6-alpha, organism-specific biosystem; Activation of Chaperone Genes by XBP1(S), organism-specific biosystem; Activation of Chaperones by ATF6-alpha, organism-specific biosystem; Activation of Chaperones by IRE1alpha, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; FOXA1 transcription factor network, organism-specific biosystem;
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Park, KS; Bayles, I; et al. Transcription Elongation Factor ELL2 Drives Ig Secretory-Specific mRNA Production and the Unfolded Protein Response. JOURNAL OF IMMUNOLOGY 193:4663-4674(2014).
Liu, L; Qi, XP; et al. Targeting the IRE1 alpha/XBP1 and ATF6 Arms of the Unfolded Protein Response Enhances VEGF Blockade to Prevent Retinal and Choroidal Neovascularization. AMERICAN JOURNAL OF PATHOLOGY 182:1412-1424(2013).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.