Anti-XBP1 monoclonal antibody (DCABH-235)

Mouse anti-Human XBP1 monoclonal antibody for WB, ELISA, IHC-P, ICC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
0C8F6
Species Reactivity
Human
Immunogen
Recombinant fragment, corresponding to amino acids 2-160 of Human XBP1
Conjugate
Unconjugated

Applications


Application Notes
WB: 0.5 - 1 μg/ml; IHC-P: 10 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
XBP1; X-box binding protein 1; XBP2; X-box-binding protein 1; tax-responsive element-binding protein 5; TREB5
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of Chaperone Genes by ATF6-alpha, organism-specific biosystem; Activation of Chaperone Genes by XBP1(S), organism-specific biosystem; Activation of Chaperones by ATF6-alpha, organism-specific biosystem; Activation of Chaperones by IRE1alpha, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; FOXA1 transcription factor network, organism-specific biosystem;

Citations


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References


Gunn, KE; Gifford, NM; et al. A role for the unfolded protein response in optimizing antibody secretion. MOLECULAR IMMUNOLOGY 41:919-927(2004).
Masciarelli, S; Fra, AM; et al. CHOP-independent apoptosis and pathway-selective induction of the UPR in developing plasma cells. MOLECULAR IMMUNOLOGY 47:1356-1365(2010).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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